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(11)

EP 4 472 682 A1

(12)

(43) Date of publication: 11.12.2024 Bulletin 2024/50 (21) Application number: 22925200.2 (22) Date of filing: 06.12.2022

(51) International Patent Classification (IPC):  A61L 9/01(2006.01) G01N 27/04(2006.01) G01N 21/78(2006.01) (52) Cooperative Patent Classification (CPC): A61L 2/232; A61L 2/28; A61L 2/238; A61L 2/235; A61L 2202/14 (86) International application number: PCT/US2022/051884 (87) International publication number: WO 2023/149947 (10.08.2023 Gazette 2023/32)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 01.02.2022 US 202263305445 P 05.12.2022 US 202218074988 (71) Applicant: HRL Laboratories, LLC Malibu, California 90265 (US)	(72) Inventors: VAJO, John West Hills, California 91307 (US) GROSS, Adam Santa Monica, California 90405 (US) GRAETZ, Jason Calabasas, California 91362 (US) (74) Representative: Coles, Andrea Birgit et al Kilburn & Strode LLP Lacon London 84 Theobalds Road London WC1X 8NL London WC1X 8NL (GB)