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EP 4 472 999 A1

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(43) Date of publication: 11.12.2024 Bulletin 2024/50 (21) Application number: 23710146.4 (22) Date of filing: 31.01.2023

(51) International Patent Classification (IPC):  C07K 7/08(2006.01) C07K 1/30(2006.01) A61K 38/00(2006.01) C07K 14/715(2006.01) (52) Cooperative Patent Classification (CPC): C07K 7/08; C07K 14/7155; A61K 38/00 (86) International application number: PCT/US2023/061651 (87) International publication number: WO 2023/150500 (10.08.2023 Gazette 2023/32)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 01.02.2022 US 202263305631 P (71) Applicant: Janssen Pharmaceutica NV 2340 Beerse (BE)

(72) Inventors: BROECKX, Geraldine 2340 Beerse (BE) BRESLIN, David T. Spring House, Pennsylvania 19477 (US) CANTO, Clara Anduix 2340 Beerse (BE) DE DOBBELAERE, Christopher Paul 2340 Beerse (BE) DENIAU, Gildas 8200 Schaffhausen (CH) DI PRETORO, Giustino Spring House, Pennsylvania 19477 (US) FERNANDES, Philippe 2340 Beerse (BE) KOLAKOVIC, Ruzica 2340 Beerse (BE) MERTENS, Nathalie 2340 Beerse (BE) PEDERSEN, Betty Lomstein 2340 Beerse (BE) RAJAN, Gopal 2340 Beerse (BE) SUN, Dajun 2340 Beerse (BE) PATEL, Sejal Spring House, Pennsylvania 19477 (US) (74) Representative: Carpmaels & Ransford LLP  One Southampton Row London WC1B 5HA London WC1B 5HA (GB)