(19)
(11) EP 4 482 373 A1

(12)

(43) Date of publication:
01.01.2025 Bulletin 2025/01

(21) Application number: 23760885.6

(22) Date of filing: 22.02.2023
(51) International Patent Classification (IPC): 
A61B 5/00(2006.01)
G16H 20/10(2018.01)
 A61B 5/02(2006.01)
(52) Cooperative Patent Classification (CPC):
A61B 5/02; G16H 20/10; A61B 5/0022; A61B 5/11; A61B 5/021; A61B 5/024; A61B 5/7264
(86) International application number:
PCT/US2023/063054
(87) International publication number:
WO 2023/164498 (31.08.2023 Gazette 2023/35)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
KH MA MD TN

(30) Priority: 25.02.2022 US 202263314207 P

(71) Applicant: Cedars-Sinai Medical Center
Los Angeles, CA 90048 (US)

(72) Inventors:
  • KHANDWALLA, Raj
    Santa Monica, CA 90405 (US)
  • SHVARTSER, Alex
    Tarzana, CA 91356 (US)

(74) Representative: Mathys & Squire 
The Shard 32 London Bridge Street
London SE1 9SG
London SE1 9SG (GB)

   


(54) COMPOSITIONS AND METHODS FOR THERAPEUTIC MANAGEMENT OF HEART FAILURE PATIENTS