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EP 4 482 980 A1

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(43) Date of publication: 01.01.2025 Bulletin 2025/01 (21) Application number: 23712432.6 (22) Date of filing: 27.02.2023

(51) International Patent Classification (IPC):  C12Q 1/6816(2018.01) C12Q 1/6886(2018.01) C12Q 1/6827(2018.01) (52) Cooperative Patent Classification (CPC): C12Q 1/6886; C12Q 2600/16; C12Q 1/6816; C12Q 1/6827; Y02A 50/30   C-Sets: C12Q 1/6816, C12Q 2537/143, C12Q 2563/131; C12Q 1/6827, C12Q 2537/143, C12Q 2563/131; (86) International application number: PCT/US2023/063380 (87) International publication number: WO 2023/164713 (31.08.2023 Gazette 2023/35)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 25.02.2022 US 202263314267 P 13.12.2022 US 202263387262 P (71) Applicant: Tempus AI, Inc. Chicago, IL 60654 (US)

(72) Inventors: BLIDNER, Richard Chicago, IL 60654 (US) KUTTAB-BOULOS, Hala, Samir Chicago, IL 60654 (US) HUETHER, Robert, Paul Chicago, IL 60654 (US) HOSKINSON, Derick Curtis Chicago, IL 60654 (US) VLANGOS, Christopher, Nicholas Chicago, IL 60654 (US) PATEL, Miral Jigar Chicago, IL 60654 (US) LONGONI, Mauro Chicago, IL 60654 (US) TELL, Robert Chicago, IL 60654 (US) LO, Christine Chicago, IL 60654 (US) ZHU, Wei Chicago, IL 60654 (US) BEAUBIER, Nike Tsiapera Chicago, IL 60654 (US) BUSH, Stephen J. Chicago, IL 60654 (US) DRY, Jonathan Chicago, IL 60654 (US) HASSANE, Duane Christopher Chicago, IL 60654 (US) (74) Representative: Grund, Martin et al Grund Intellectual Property Group Patentanwälte und Solicitor PartG mbB Steinsdorfstraße 2 80538 München 80538 München (DE)