(19)

(11)

EP 4 486 309 A1

(12)

(43) Date of publication: 08.01.2025 Bulletin 2025/02 (21) Application number: 23707384.6 (22) Date of filing: 27.02.2023

(51) International Patent Classification (IPC):  A61K 9/16(2006.01) A61K 31/549(2006.01) (52) Cooperative Patent Classification (CPC): A61K 31/549; A61K 9/1688 (86) International application number: PCT/EP2023/054884 (87) International publication number: WO 2023/161493 (31.08.2023 Gazette 2023/35)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 28.02.2022 EP 22461508 (71) Applicant: Zaklady Farmaceutyczne Polpharma S.A. 83-200 Starogard Gdanski (PL)	(72) Inventors: SAGOL, Karol 83-110 Tczew (PL) KRZYZANOWSKI, Mariusz 83-200 Skorcz (PL) WIELESIK, Cezary 83-200 Starogard Gdanski (PL) (74) Representative: Rechnio, Justyna Tatiana  Zaklady Farmaceutyczne Polpharma S.A. Ul. Pelplinska 19 83-200 Starogard Gdanski 83-200 Starogard Gdanski (PL)