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EP 4 486 348 A1

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(43) Date of publication: 08.01.2025 Bulletin 2025/02 (21) Application number: 23707768.0 (22) Date of filing: 02.03.2023

(51) International Patent Classification (IPC):  A61K 31/506(2006.01) A61K 31/585(2006.01) A61P 35/00(2006.01) A61K 31/5377(2006.01) C07D 401/12(2006.01) C07D 413/12(2006.01) A61K 31/4045(2006.01) A61K 45/06(2006.01) A61K 31/505(2006.01) C07D 239/48(2006.01) C07D 403/12(2006.01) C07D 417/14(2006.01) (52) Cooperative Patent Classification (CPC): A61P 35/00; A61K 31/506; A61K 31/4045; A61K 31/585; A61K 45/06; A61K 31/505; A61K 31/5377; C07D 239/48; C07D 401/12; C07D 403/12; C07D 413/12; C07D 417/14   C-Sets: A61K 31/5377, A61K 2300/00; A61K 31/4045, A61K 2300/00; A61K 31/585, A61K 2300/00; A61K 31/506, A61K 2300/00; A61K 31/505, A61K 2300/00; (86) International application number: PCT/EP2023/055381 (87) International publication number: WO 2023/166153 (07.09.2023 Gazette 2023/36)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 02.03.2022 EP 22159838 (71) Applicant: Trustlife Global Inc. San Diego, CA 92101 (US)	(72) Inventors: LI, Xiangyu 113 46 Stockholm (SE) BOUZIAN, Younos 34774 Ümraniye/Istanbul (TR) EL HAFI, Mohamed 34774 Ümraniye/Istanbul (TR) PARVIZI, Negar 34774 Ümraniye/Istanbul (TR) MARDINOGLU, Adil 412 60 Göteborg (SE) (74) Representative: Kransell & Wennborg KB  P.O. Box 27834 115 93 Stockholm 115 93 Stockholm (SE)