(19)
(11) EP 4 489 772 A1

(12)

(43) Date of publication:
15.01.2025 Bulletin 2025/03

(21) Application number: 23767652.3

(22) Date of filing: 08.03.2023
(51) International Patent Classification (IPC): 
A61K 38/43(2006.01)
A61K 35/76(2015.01)
A61K 38/46(2006.01)
A61K 48/00(2006.01)
 C12N 5/10(2006.01)
C12N 9/50(2006.01)
A61K 38/48(2006.01)
(52) Cooperative Patent Classification (CPC):
C12N 2740/16043; C12N 9/22; C07K 14/005; C12N 15/86; C12N 2795/18122; C12N 2795/10322; C12N 2310/20; C12N 9/1252; C12N 15/90; C12Y 207/07007; C07K 2319/00
(86) International application number:
PCT/US2023/063954
(87) International publication number:
WO 2023/172966 (14.09.2023 Gazette 2023/37)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
KH MA MD TN

(30) Priority: 08.03.2022 US 202263317720 P

(71) Applicant: Wake Forest University Health Sciences
Winston-Salem, NC 27157 (US)

(72) Inventors:
  • LU, Baisong
    Winston-Salem, NC 27106 (US)
  • ATALA, Anthony
    Winston-Salem, NC 27104 (US)

(74) Representative: Forresters IP LLP 
Skygarden Erika-Mann-Straße 11
80636 München
80636 München (DE)

   


(54) COMPOSITIONS, SYSTEMS AND METHODS FOR EUKARYOTIC GENE EDITING