(19)

(11)

EP 4 490 288 A2

(12)

(88) Date of publication A3: 23.11.2023 (43) Date of publication: 15.01.2025 Bulletin 2025/03 (21) Application number: 23767727.3 (22) Date of filing: 10.03.2023

(51) International Patent Classification (IPC):  C12N 15/11(2006.01) C12N 15/10(2006.01) C12N 15/63(2006.01) C12N 9/22(2006.01) C12N 15/113(2010.01) (52) Cooperative Patent Classification (CPC): C12N 15/86; C12N 15/62; C12Q 1/6806; C12Q 1/683; C12N 15/102; C12N 2310/20; C12N 9/22; C07K 2319/09; C12N 2740/16043; C12N 15/1138; C12N 15/907   C-Sets: C12Q 1/6806, C12Q 2521/301; C12Q 1/683, C12Q 2521/301; (86) International application number: PCT/US2023/064097 (87) International publication number: WO 2023/173062 (14.09.2023 Gazette 2023/37)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 11.03.2022 US 202263318906 P 10.01.2023 US 202363479274 P (71) Applicant: Intima Bioscience, Inc. New York, New York 10019 (US)	(72) Inventors: BUERCKSTUEMMER, Tilmann 1050 Wien (AT) SCHMIDT, Henrik 1030 Wien (AT) SIEBER, Anna 1030 Wien (AT) ILSINGER, Christoph 1030 Wien (AT) (74) Representative: J A Kemp LLP  80 Turnmill Street London EC1M 5QU London EC1M 5QU (GB)