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EP 4 493 587 A1

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(43) Date of publication: 22.01.2025 Bulletin 2025/04 (21) Application number: 23715415.8 (22) Date of filing: 14.03.2023

(51) International Patent Classification (IPC):  C07K 16/18(2006.01) A61P 35/00(2006.01) C07K 14/725(2006.01) C07K 16/30(2006.01) A61K 39/00(2006.01) (52) Cooperative Patent Classification (CPC): A61K 39/4631; A61K 39/4611; A61P 35/00; C07K 2317/622; C07K 2319/03; C07K 16/18; C07K 16/30; C07K 14/4702 (86) International application number: PCT/EP2023/056397 (87) International publication number: WO 2023/174897 (21.09.2023 Gazette 2023/38)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 14.03.2022 EP 22161839 (71) Applicants: Helmholtz Zentrum Muenchen - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) 85764 Neuherberg (DE) Eximmium Biotechnologies GmbH 81377 Munich (DE) Klinikum der Universitaet Muenchen 81377 Munich (DE)

(72) Inventors: ZEIDLER, Reinhard 82140 Olching (DE) GAERTNER, Kathrin 81547 Munich (DE) (74) Representative: Schiweck Weinzierl Koch Patentanwälte Partnerschaft mbB  Ganghoferstraße 68 B 80339 München 80339 München (DE)