(57) A novel composition is proposed for a water-based care solution that may be employed for increasing the hygiene of intraoral appliances such as dental splints. By immersing such an appliance into said care solution, different active agents contained in the care solution can be rapidly loaded at sufficiently high amounts into the device, in particular if the device shows a highly porous surface due to an underlying 3D-printing fabrication process. Accordingly, once reloaded, the dental appliance can release the different agents into the oral cavity to achieve an antimicrobial effect inside the oral cavity and the agents remaining in the pores of the device can prevent microorganisms from growing on or inside the appliance.