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EP 4 499 225 A1

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(43) Date of publication: 05.02.2025 Bulletin 2025/06 (21) Application number: 23778704.9 (22) Date of filing: 30.03.2023

(51) International Patent Classification (IPC):  A61P 25/16(2006.01) A61K 35/17(2025.01) A61P 25/28(2006.01) (52) Cooperative Patent Classification (CPC): A61P 25/16; A61K 36/06; A61K 36/88; A61K 31/201 (86) International application number: PCT/IN2023/050315 (87) International publication number: WO 2023/187838 (05.10.2023 Gazette 2023/40)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 30.03.2022 IN 202211019288 (71) Applicants: Council of Scientific and Industrial Research, an Indian Registered Body Incorporated under Regn. of Soc. Act (Act XXI of 1860) New Delhi, Delhi 110 001 (IN) National Institute of Mental Health and Neurosciences (NIMHANS) Bangalore 560029 (IN)

(72) Inventors: B., Padmanabhan Karnataka Bangalore 560029 (IN) ASIF, Ali Delhi 110007 (IN) DESHMUKH, Prashant Karnataka Bangalore 560029 (IN) UNNI, Sruthi Karnataka Bangalore 560029 (IN) YEDUKONDALU, Nalli Jammu (IN) M M, Srinivas Bharath Karnataka Bangalore 560029 (IN) RIYAZ-UL-HASSAN, Syed Jammu (IN) AHMED, Wani Zahoor Jammu (IN) (74) Representative: Nederlandsch Octrooibureau  P.O. Box 29720 2502 LS The Hague 2502 LS The Hague (NL)