(19)

(11)

EP 4 499 638 A1

(12)

(43) Date of publication: 05.02.2025 Bulletin 2025/06 (21) Application number: 23722227.8 (22) Date of filing: 24.03.2023

(51) International Patent Classification (IPC):  C07D 471/04(2006.01) A61P 25/00(2006.01) A61K 31/5025(2006.01) (52) Cooperative Patent Classification (CPC): C07D 471/04 (86) International application number: PCT/US2023/064967 (87) International publication number: WO 2023/183943 (28.09.2023 Gazette 2023/39)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 25.03.2022 US 202217704983 31.10.2022 US 202263420930 P 07.02.2023 US 202363443874 P (71) Applicant: Ventus Therapeutics U.S., Inc. Waltham, MA 02453 (US)	(72) Inventors: DORICH, Stéphane Pointe-Claire, Québec H9R 1H6 (CA) CHEFSON, Amandine Montreal, Québec H4E 2W8 (CA) CIBLAT, Stéphane Montreal, Québec H2J 0A2 (CA) (74) Representative: Schlich  9 St Catherine's Road Littlehampton West Sussex BN17 5HS West Sussex BN17 5HS (GB)