(19)
(11) EP 4 504 169 A1

(12)

(43) Date of publication:
12.02.2025 Bulletin 2025/07

(21) Application number: 22970305.3

(22) Date of filing: 30.12.2022
(51) International Patent Classification (IPC): 
A61K 31/365(2006.01)
 A61P 43/00(2006.01)
(52) Cooperative Patent Classification (CPC):
A61K 31/343; C07D 307/93
(86) International application number:
PCT/TR2022/051702
(87) International publication number:
WO 2024/144481 (04.07.2024 Gazette 2024/27)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
KH MA MD TN

(71) Applicant: Istinye Üniversitesi
34010 Zeytinburnu Istanbul (TR)

(72) Inventors:
  • MISKI, Mahmud
    34116 Fatih/ stanbul (TR)
  • ERUCAR, Fatma Memnune
    34116 Fatih/ stanbul (TR)
  • TAN, Nur
    34116 stanbul (TR)
  • GÜLEÇ, Meltem
    Avc lar/ (TR)
  • OLGUN, Abdullah
    34375 i li/ stanbul (TR)

(74) Representative: Yalçiner Patent and Consulting Ltd. 
Tunus Caddesi 85/3-4 Kavaklidere
06680 Ankara
06680 Ankara (TR)

   


(54) NATURALLY OCCURRING SESQUITERPENE LACTONE THAT PROLONGS LIFESPAN ON AN IN VIVO MODEL OF CAENORHABDITIS ELEGANS: GERMINOLIDE