(19)
(11) EP 4 509 153 A3

(12) EUROPEAN PATENT APPLICATION

(88) Date of publication A3:
16.04.2025 Bulletin 2025/16

(43) Date of publication A2:
19.02.2025 Bulletin 2025/08

(21) Application number: 24222652.0

(22) Date of filing: 23.05.2018
(51) International Patent Classification (IPC): 
A61M 5/20(2006.01)
 A61M 5/315(2006.01)
(52) Cooperative Patent Classification (CPC):
A61M 5/19; A61M 5/20; A61M 5/2066; A61M 5/315; A61M 5/31511; A61M 5/31576; A61M 5/31596; A61M 2005/2013; A61M 2005/2026; A61M 2005/3152; A61M 2005/31588; A61M 2205/103; A61M 2205/215; A61M 2205/332; A61M 2205/3365; A61M 2205/50; A61M 2205/6081
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(30) Priority: 23.05.2017 EP 17172456

(62) Application number of the earlier application in accordance with Art. 76 EPC:
18724904.0 / 3630232

(71) Applicant: Ascendis Pharma A/S
2900 Hellerup (DK)

(72) Inventors:
  • EGESBORG, Henrik
    2900 Hellerup (DK)
  • JENSEN, Steen
    2900 Hellerup (DK)
  • LARSEN, Martin Nørgaard
    7600 Struer (DK)
  • ELKJÆR, Johnny
    7600 Struer (DK)
  • ANDERSEN, Bjørn Knud
    7600 Struer (DK)

(74) Representative: Zacco Denmark A/S 
Arne Jacobsens Allé 15
2300 Copenhagen S
2300 Copenhagen S (DK)

   


(54) AUTO INJECTOR WITH VARIABLE PLUNGER FORCE


(57) Disclosed is a method and an auto-injector for administering a medicament. The auto injector comprising: a housing; a cartridge receiver configured to receive a cartridge comprising a first stopper; a drive module coupled to move a plunger rod between a retracted plunger rod position and an extended plunger rod position, the plunger rod being configured to move the first stopper; a resistance sensor configured to provide a resistance signal indicative of resistance against movement of the plunger rod; and a processing unit coupled to the drive module and to the resistance sensor. The processing unit being configured to: control the drive module to move the plunger rod towards the extended plunger rod position with a plunger rod speed; determine plunger rod position; receive the resistance signal; and control the drive module to adjust movement of the plunger rod if the resistance signal is indicative of resistance against movement of the plunger rod above a high resistance threshold, wherein the high resistance threshold is based on the plunger rod position.







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Search report