(19)

(11)

EP 4 511 054 A2

(12)

(88) Date of publication A3: 30.11.2023 (43) Date of publication: 26.02.2025 Bulletin 2025/09 (21) Application number: 23792786.8 (22) Date of filing: 20.04.2023

(51) International Patent Classification (IPC):  A61K 38/20(2006.01) A61P 35/00(2006.01) A61K 38/19(2006.01) A61K 38/16(2006.01) (52) Cooperative Patent Classification (CPC): C07K 14/54; C07K 2319/30; C07K 2319/31; C12N 15/62; A61K 38/00 (86) International application number: PCT/US2023/066016 (87) International publication number: WO 2023/205738 (26.10.2023 Gazette 2023/43)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 20.04.2022 US 202263333085 P 20.04.2022 US 202263333090 P (71) Applicant: Neptune Biosciences LLC Newark, CA 94560 (US)	(72) Inventors: KILLEEN, Nigel Hillsborough, CA 94010 (US) BESKE, Oren Aromas, CA 95004 (US) VOLLRATH, Benedikt, K. San Diego, CA 92107 (US) GOVINDARAJAN, Sridhar Los Altos, CA 94024 (US) (74) Representative: Forresters IP LLP  Skygarden Erika-Mann-Straße 11 80636 München 80636 München (DE)