(19)
(11) EP 4 512 829 A8

(12) CORRECTED EUROPEAN PATENT APPLICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 A2)

(48) Corrigendum issued on:
16.04.2025 Bulletin 2025/16

(43) Date of publication:
26.02.2025 Bulletin 2025/09

(21) Application number: 24210762.1

(22) Date of filing: 13.07.2017
(51) International Patent Classification (IPC): 
C07K 16/28(2006.01)
(52) Cooperative Patent Classification (CPC):
A61K 2039/507; C07K 2317/21; C07K 2317/41; C07K 2317/55; C07K 2317/71; C07K 2317/74; A61K 2039/505; C07K 16/2803; C07K 2317/33; C07K 2317/34; C07K 2317/76; C07K 2317/92; C07K 2317/94; A61P 35/00
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
MA

(30) Priority: 14.07.2016 US 201662362541 P
15.02.2017 US 201762459499 P

(62) Application number of the earlier application in accordance with Art. 76 EPC:
17742626.9 / 3484920

(71) Applicant: Bristol-Myers Squibb Company
Princeton, NJ 08543 (US)

(72) Inventors:
  • SCHEBYE, Xiao Min
    Redwood City, 94063 (US)
  • SELBY, Mark J.
    Redwood City, 94063 (US)
  • HAN, Michelle Minhua
    Redwood City, 94063 (US)
  • BEE, Christine
    Redwood City, 94063 (US)
  • DENG, Andy X.
    Redwood City, 94063 (US)
  • CHUNTHARAPAI, Anan
    Redwood City, 94063 (US)
  • DEVAUX, Brigitte
    Palo Alto, 94306 (US)
  • LI, Huiming
    Lexington, 02420 (US)
  • SHEPPARD, Paul O.
    Granite Falls, 98252 (US)
  • KORMAN, Alan J.
    Redwood City, 94063 (US)
  • ARDOUREL, Daniel F.
    Woodinville, 98077 (US)
  • DEYANOVA, Ekaterina
    Princeton, 08543 (US)
  • HUANG, Richard
    Princeton, 08543 (US)
  • CHEN, Guodong
    Princeton, 08543 (US)
  • KUHNE, Michelle
    Redwood City, 94063 (US)
  • TRUONG, Hong-An
    Redwood City, 94063 (US)

(74) Representative: Mewburn Ellis LLP 
Aurora Building Counterslip
Bristol BS1 6BX
Bristol BS1 6BX (GB)

 
Remarks:
The complete document including Reference Table(s) and the Sequence Listing(s) can be downloaded from the EPO website
Remarks:
This application was filed on 05-11-2024 as a divisional application to the application mentioned under INID code 62.
Remarks:
Claims filed after the date of filing of the application/after the date of receipt of the divisional application (Rule 68(4) EPC).
 


(54) ANTIBODIES AGAINST TIM3 AND USES THEREOF


(57) Provided herein are antibodies, or antigen-binding portions thereof, that bind to T-cell immunoglobulin and mucin-domain containing-3 (TIM3) protein. Also provided are uses of these antibodies, or antigen-binding portions thereof, in therapeutic applications, such as treatment of cancer. Further provided are cells that produce the antibodies, or antigen-binding portions thereof, polynucleotides encoding the heavy and/or light chain regions of the antibodies, or antigen-binding portions thereof, and vectors comprising the polynucleotides encoding the heavy and/or light chain regions of the antibodies, or antigen-binding portions thereof.