(19)
(11) EP 4 518 835 A1

(12)

(43) Date of publication:
12.03.2025 Bulletin 2025/11

(21) Application number: 23724023.9

(22) Date of filing: 21.04.2023
(51) International Patent Classification (IPC): 
A61K 9/00(2006.01)
A61K 33/14(2006.01)
A61K 47/18(2017.01)
A61M 1/28(2006.01)
A61K 31/7004(2006.01)
A61K 47/10(2017.01)
A61K 47/26(2006.01)
A61P 7/08(2006.01)
(52) Cooperative Patent Classification (CPC):
A61K 9/0019; A61K 47/10; A61K 47/18; A61K 47/26; A61K 31/7004; A61K 33/14; A61M 1/287; A61P 7/08; A61K 31/718; A61K 33/06; A61K 31/047; A61K 31/198; A61K 31/17; A61K 31/78; A61K 31/785; A61K 31/704; A61K 31/205
 
C-Sets:
  1. A61K 31/047, A61K 2300/00;
  2. A61K 31/198, A61K 2300/00;
  3. A61K 31/17, A61K 2300/00;
  4. A61K 31/78, A61K 2300/00;
  5. A61K 31/785, A61K 2300/00;
  6. A61K 31/7004, A61K 2300/00;
  7. A61K 31/205, A61K 2300/00;
  8. A61K 31/718, A61K 2300/00;
  9. A61K 31/704, A61K 2300/00;
  10. A61K 33/14, A61K 2300/00;
  11. A61K 33/06, A61K 2300/00;

(86) International application number:
PCT/IB2023/054061
(87) International publication number:
WO 2023/214238 (09.11.2023 Gazette 2023/45)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
KH MA MD TN

(30) Priority: 02.05.2022 US 202217661737
20.01.2023 US 202318157741

(71) Applicant: Sequana Medical NV
9051 Sint-Denijs Westrem (BE)

(72) Inventors:
  • TESTANI, Jeffrey
    Guilford, Connecticut 06437 (US)
  • MCINTYRE, Christopher
    London, Ontario N6A3W6 (CA)
  • CROSBIE, Ian
    London W11 4LH (GB)
  • GOEDJE, Oliver
    82064 Strasslach (DE)

(74) Representative: Vossius & Partner Patentanwälte Rechtsanwälte mbB 
Siebertstrasse 3
81675 München
81675 München (DE)

   


(54) FORMULATIONS AND METHODS FOR DIRECT SODIUM REMOVAL IN PATIENTS HAVING HEART FAILURE AND/OR SEVERE RENAL DYSFUNCTION