(19)
(11) EP 4 518 977 A1

(12)

(43) Date of publication:
12.03.2025 Bulletin 2025/11

(21) Application number: 23800035.0

(22) Date of filing: 04.05.2023
(51) International Patent Classification (IPC): 
A61Q 19/00(2006.01)
A61L 27/48(2006.01)
 A61L 27/52(2006.01)
A61L 27/26(2006.01)
(52) Cooperative Patent Classification (CPC):
A61L 27/52; A61L 2400/06; A61L 2430/36; A61L 27/50; B33Y 80/00; A61L 27/20; A61L 27/222
 
C-Sets:
A61L 27/20, C08L 5/04;
(86) International application number:
PCT/US2023/021006
(87) International publication number:
WO 2023/215479 (09.11.2023 Gazette 2023/45)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
KH MA MD TN

(30) Priority: 04.05.2022 US 202263338285 P

(71) Applicants:
  • MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Cambridge, MA 02139 (US)
  • President And Fellows Of Harvard College
    Cambridge, Massachusetts 02138 (US)

(72) Inventors:
  • MENDEZ, Keegan
    Cambrdige, Massachusetts 02139 (US)
  • ROCHE, Ellen
    Cambridge, Massachusetts 02139 (US)
  • VERHEYEN, Connor
    Cambridge, Massachusetts 02139 (US)
  • LEWIS, Jennifer
    Quincy Street Cambrdige, Massachusetts 02138 (US)
  • HORVATH, Markus
    Cambridge, Massachusetts 02139 (US)
  • WANG, Sophie
    Cambridge, Massachusetts 02139 (US)
  • UZEL, Sebastien
    Cambridge, Massachusetts 02138 (US)

(74) Representative: Hoffmann Eitle 
Patent- und Rechtsanwälte PartmbB Arabellastraße 30
81925 München
81925 München (DE)

   


(54) FORMULATIONS AND MEDICAL DEVICES FOR MINIMALLY-INVASIVE DEEP TISSUE APPLICATIONS