(19)

(11)

EP 4 522 118 A2

(12)

(88) Date of publication A3: 21.12.2023 (43) Date of publication: 19.03.2025 Bulletin 2025/12 (21) Application number: 23731477.8 (22) Date of filing: 11.05.2023

(51) International Patent Classification (IPC):  A61K 9/00(2006.01) A61K 47/26(2006.01) A61K 38/08(2019.01) A61K 47/02(2006.01) A61K 38/00(2006.01) A61P 27/02(2006.01) (52) Cooperative Patent Classification (CPC): A61K 9/0048; A61K 47/26; A61K 47/02; A61K 38/08; A61P 27/02; A61P 29/00 (86) International application number: PCT/US2023/066879 (87) International publication number: WO 2023/220676 (16.11.2023 Gazette 2023/46)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 12.05.2022 US 202263341205 P 20.12.2022 US 202263434042 P (71) Applicant: Okyo Pharma Limited St Peter Port, Guernsey, GY1 3HB (GG)	(72) Inventor: PATIL, Rajkumar V. Keller, Texas 76248 (US) (74) Representative: Cooley (UK) LLP  22 Bishopsgate London EC2N 4BQ London EC2N 4BQ (GB)