(19)

(11)

EP 4 522 147 A1

(12)

(43) Date of publication: 19.03.2025 Bulletin 2025/12 (21) Application number: 23729228.9 (22) Date of filing: 09.05.2023

(51) International Patent Classification (IPC):  A61K 31/201(2006.01) A61P 21/00(2006.01) A61K 31/202(2006.01) A61P 25/28(2006.01) (52) Cooperative Patent Classification (CPC): A61K 31/202; A61K 31/201; A61P 25/28; A61P 21/00 (86) International application number: PCT/US2023/021543 (87) International publication number: WO 2023/220058 (16.11.2023 Gazette 2023/46)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 09.05.2022 US 202263339927 P (71) Applicant: Biojiva LLC San Jose, CA 95134 (US)	(72) Inventors: MILNER, Peter San Jose, CA 95134 (US) LITTERMAN, Nadia San Jose, CA 95134 (US) MIDEI, Mark San Jose, CA 95134 (US) (74) Representative: Sagittarius IP  Marlow International Parkway Marlow SL7 1YL Marlow SL7 1YL (GB)