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EP 4 529 468 A1

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(43) Date of publication: 02.04.2025 Bulletin 2025/14 (21) Application number: 23723994.2 (22) Date of filing: 22.05.2023

(51) International Patent Classification (IPC):  A61K 47/54(2017.01) A61K 47/69(2017.01) A61K 38/08(2019.01) A61K 38/29(2006.01) A61K 49/00(2006.01) A61P 31/04(2006.01) A61K 45/06(2006.01) A61K 9/00(2006.01) A61K 38/14(2006.01) A61K 38/38(2006.01) A61P 19/10(2006.01) A61P 35/00(2006.01) (52) Cooperative Patent Classification (CPC): A61K 49/0021; A61K 49/0034; A61K 49/006; A61K 49/0054; A61K 49/0073; A61P 31/04; A61K 9/0024; A61K 38/14; A61K 38/29; A61P 19/10; A61P 35/00; A61K 45/06; A61K 47/541; A61K 47/6903; A61K 47/542; A61K 47/544; A61K 31/7036; A61K 31/7056 (86) International application number: PCT/EP2023/063626 (87) International publication number: WO 2023/227517 (30.11.2023 Gazette 2023/48)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 23.05.2022 EP 22174814 (71) Applicant: Danmarks Tekniske Universitet 2800 Kongens Lyngby (DK)

(72) Inventors: ANDRESEN, Thomas Lars 2800 Kongens Lyngby (DK) HENRIKSEN, Jonas Rosager 2800 Kongens Lyngby (DK) HANSEN, Anders Elias 2800 Kongens Lyngby (DK) FUGLSANG-MADSEN, Albert Juan 2800 Kongens Lyngby (DK) SERRANO CHÁVEZ, Elizabeth 2800 Kongens Lyngby (DK) BJÖRGVINSDÓTTIR, Unnur Jóna 2800 Kongens Lyngby (DK) LI, Xin 2800 Kongens Lyngby (DK) (74) Representative: AWA Sweden AB  Matrosgatan 1 Box 5117 200 71 Malmö 200 71 Malmö (SE)