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(11)

EP 4 531 851 A1

(12)

(43) Date of publication: 09.04.2025 Bulletin 2025/15 (21) Application number: 23735395.8 (22) Date of filing: 01.06.2023

(51) International Patent Classification (IPC):  A61K 31/4439(2006.01) A61P 25/24(2006.01) A61K 45/06(2006.01) A61K 9/00(2006.01) (52) Cooperative Patent Classification (CPC): A61K 31/4439; A61P 25/24; A61K 45/06; A61K 9/0019; A61K 9/19; A61K 9/08   C-Sets: A61K 31/4439, A61K 2300/00; (86) International application number: PCT/IB2023/055651 (87) International publication number: WO 2023/233357 (07.12.2023 Gazette 2023/49)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 02.06.2022 US 202263365749 P (71) Applicant: Novartis AG 4056 Basel (CH)	(72) Inventors: FALLER, Thomas Herbert 4002 Basel (CH) KOEHNE-VOSS, Stephan Josef 4002 Basel (CH) KORADIA, Vishal Shamji 4002 Basel (CH) PAPANICOLAOU, Dimitris Angelo East Hanover, New Jersey 07936 (US) SERBAN, Carmen-Gabriela 4002 Basel (CH) (74) Representative: Potter Clarkson  Chapel Quarter Mount Street Nottingham NG1 6HQ Nottingham NG1 6HQ (GB)