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EP 4 531 864 A1

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(43) Date of publication: 09.04.2025 Bulletin 2025/15 (21) Application number: 23812820.1 (22) Date of filing: 26.05.2023

(51) International Patent Classification (IPC):  A61K 31/565(2006.01) A61K 9/22(2006.01) A61P 43/00(2006.01) A61K 9/08(2006.01) A61K 31/568(2006.01) (52) Cooperative Patent Classification (CPC): A61K 31/565; A61K 31/568; A61K 9/0024   C-Sets: A61K 31/565, A61K 2300/00; A61K 31/568, A61K 2300/00; (86) International application number: PCT/US2023/067568 (87) International publication number: WO 2023/230621 (30.11.2023 Gazette 2023/48)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 26.05.2022 US 202263365389 P 03.10.2022 US 202217937740 03.10.2022 US 202263378227 P (71) Applicant: Insigna Inc. Champaign IL 61820 (US)	(72) Inventors: KO, CheMyong Champaign, IL 61822 (US) PARK, ChanJin Savoy, IL 61874 (US) HESS, Rex Allen Champaign, IL 61821 (US) LIN, Po-Ching Patrick Champaign, IL 61822 (US) (74) Representative: Lucas, Phillip Brian  Lucas & Co. 135 Westhall Road Warlingham, Surrey CR6 9HJ Warlingham, Surrey CR6 9HJ (GB)