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EP 4 531 903 A1

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(43) Date of publication: 09.04.2025 Bulletin 2025/15 (21) Application number: 23728760.2 (22) Date of filing: 25.05.2023

(51) International Patent Classification (IPC):  A61K 39/12(2006.01) A61P 31/14(2006.01) C12N 15/86(2006.01) A61K 39/215(2006.01) C12N 7/00(2006.01) (52) Cooperative Patent Classification (CPC): C12N 15/86; A61K 39/12; A61P 31/14; C07K 14/005; C12N 2770/20022; C12N 2770/20034; C12N 2760/18843; C12N 2760/18822 (86) International application number: PCT/EP2023/064144 (87) International publication number: WO 2023/227758 (30.11.2023 Gazette 2023/48)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 25.05.2022 EP 22175583 (71) Applicant: Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. 80539 München (DE)	(72) Inventors: FÄSSLER, Reinhard 82152 Martinsried (DE) NEUBERT, Wolfgang 82152 Martinsried (DE) WIEGAND, Marian 81541 München (DE) LAUER, Ulrich M. 72072 Tübingen (DE) (74) Representative: Zwicker, Jörk  ZSP Patentanwälte PartG mbB Hansastraße 32 80686 München 80686 München (DE)