(19)

(11)

EP 4 532 533 A2

(12)

(88) Date of publication A3: 07.12.2023 (43) Date of publication: 09.04.2025 Bulletin 2025/15 (21) Application number: 23816783.7 (22) Date of filing: 02.06.2023

(51) International Patent Classification (IPC):  C07K 14/705(2006.01) A61K 39/00(2006.01) (52) Cooperative Patent Classification (CPC): C07K 16/18; C07K 2317/31; A61P 21/04; A61K 2039/545; A61K 2039/505; C07K 2319/00 (86) International application number: PCT/US2023/024252 (87) International publication number: WO 2023/235545 (07.12.2023 Gazette 2023/49)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 03.06.2022 US 202263348622 P (71) Applicant: Alexion Pharmaceuticals, Inc. Boston, MA 02210 (US)	(72) Inventor: ORTIZ, Stephan Boston, Massachusetts 02210 (US) (74) Representative: J A Kemp LLP  80 Turnmill Street London EC1M 5QU London EC1M 5QU (GB)