(19)

(11)

EP 4 536 841 A2

(12)

(88) Date of publication A3: 25.01.2024 (43) Date of publication: 16.04.2025 Bulletin 2025/16 (21) Application number: 23738131.4 (22) Date of filing: 09.06.2023

(51) International Patent Classification (IPC):  C12P 19/04(2006.01) C12N 9/10(2006.01) C12P 19/18(2006.01) (52) Cooperative Patent Classification (CPC): C12P 19/04; C12P 19/18; C12N 9/1051; C12N 9/1074; C12Y 204/01001; C12Y 204/01004; C12Y 204/01007; C12Y 204/01019 (86) International application number: PCT/IB2023/055978 (87) International publication number: WO 2023/238100 (14.12.2023 Gazette 2023/50)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 10.06.2022 WO PCT/CN2022/098225 (71) Applicant: Beren Therapeutics P.B.C. West Hollywood, CA 90069 (US)	(72) Inventors: GROBAN, Eli San Francisco, California 94118 (US) HU, Karl Jiangsu 215600 (CN) PFEIFFER, Steven Hollywood, CA 90069 (US) RIZKIN, Benjamin Hollywood, CA 90069 (US) BENKOVICS, Gabor Hollywood, California 90069 (US) (74) Representative: Carpmaels & Ransford LLP  One Southampton Row London WC1B 5HA London WC1B 5HA (GB)