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(11)

EP 4 539 825 A1

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(43) Date of publication: 23.04.2025 Bulletin 2025/17 (21) Application number: 23734204.3 (22) Date of filing: 19.06.2023

(51) International Patent Classification (IPC):  A61K 9/24(2006.01) A61K 31/41(2006.01) A61K 31/404(2006.01) A61K 9/20(2006.01) (52) Cooperative Patent Classification (CPC): A61K 9/209; A61K 9/2095; A61K 31/41; A61K 31/404 (86) International application number: PCT/EP2023/066451 (87) International publication number: WO 2023/247435 (28.12.2023 Gazette 2023/52)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 20.06.2022 EP 22179833 (71) Applicant: KRKA, D.D., Novo Mesto 8501 Novo mesto (SI)	(72) Inventors: KASTELIC, Spela 8501 Novo mesto (SI) ZADNIK, Jernej 8501 Novo mesto (SI) HROVAT, Irena 8501 Novo mesto (SI) BARIC, Miha 8501 Novo mesto (SI) SMODIS, Domen 8501 Novo mesto (SI) (74) Representative: Kutzenberger Wolff & Partner  Waidmarkt 11 50676 Köln 50676 Köln (DE)