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(11)

EP 4 539 882 A1

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(43) Date of publication: 23.04.2025 Bulletin 2025/17 (21) Application number: 23823225.0 (22) Date of filing: 15.06.2023

(51) International Patent Classification (IPC):  A61K 39/395(2006.01) C07K 16/24(2006.01) A61P 35/00(2006.01) C07K 16/28(2006.01) (52) Cooperative Patent Classification (CPC): C07K 16/2803; A61K 2039/55; A61K 2039/507; A61K 2039/54; A61K 2039/545; C07K 16/2818; C07K 16/2887; C07K 2317/56; C07K 2317/52 (86) International application number: PCT/CN2023/100462 (87) International publication number: WO 2023/241659 (21.12.2023 Gazette 2023/51)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 16.06.2022 WO PCT/CN2022/099068 (71) Applicant: BeiGene, Ltd. Grand Cayman KY1-1108 (KY)	(72) Inventor: LI, Xiaotong Beijing 102206 (CN) (74) Representative: Mewburn Ellis LLP  Aurora Building Counterslip Bristol BS1 6BX Bristol BS1 6BX (GB)