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(11)

EP 4 540 380 A1

(12)

(43) Date of publication: 23.04.2025 Bulletin 2025/17 (21) Application number: 23733312.5 (22) Date of filing: 16.06.2023

(51) International Patent Classification (IPC):  C12N 9/88(2006.01) C12N 15/81(2006.01) C12N 9/02(2006.01) C12P 5/00(2006.01) (52) Cooperative Patent Classification (CPC): C12N 9/88; C12N 9/0071; C12N 15/81; C12P 5/007; C12N 9/0042; C12Y 106/02004; C12Y 402/03138 (86) International application number: PCT/EP2023/066249 (87) International publication number: WO 2023/242403 (21.12.2023 Gazette 2023/51)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 16.06.2022 EP 22179430 (71) Applicant: Danmarks Tekniske Universitet 2800 Kongens Lyngby (DK)	(72) Inventors: BORODINA, Irina 2800 Kongens Lyngby (DK) ARNESEN, Jonathan Asmund 2800 Kongens Lyngby (DK) DYEKJÆR, Jane Dannow 2800 Kongens Lyngby (DK) (74) Representative: Høiberg P/S  Adelgade 12 1304 Copenhagen K 1304 Copenhagen K (DK)