(19)
(11) EP 4 543 853 A1

(12)

(43) Date of publication:
30.04.2025 Bulletin 2025/18

(21) Application number: 23830223.6

(22) Date of filing: 27.06.2023
(51) International Patent Classification (IPC): 
C07D 207/12(2006.01)
C12N 15/113(2010.01)
 A61K 48/00(2006.01)
(52) Cooperative Patent Classification (CPC):
A61P 3/00; C07D 207/12; A01K 2207/15; A01K 2217/05; A01K 2227/105; A01K 2267/0318; C07D 235/12; C07D 403/14; C07D 235/08; C07D 403/04; C12N 15/111; C12N 2310/11; C12N 2310/351; C12N 2310/3515; C12N 2320/32; C12N 2310/14; C12N 2310/315; C12N 2310/3341; C12N 2310/3183; C07H 15/26; C07H 21/00; A61K 47/549; A61K 47/545; A61K 47/542
 
C-Sets:
  1. C12N 2310/321, C12N 2310/3521;
  2. C12N 2310/322, C12N 2310/3533;
  3. C12N 2310/321, C12N 2310/3525;
(86) International application number:
PCT/CN2023/102623
(87) International publication number:
WO 2024/002046 (04.01.2024 Gazette 2024/01)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
KH MA MD TN

(30) Priority: 27.06.2022 WO PCT/CN2022/101636
11.08.2022 WO PCT/CN2022/111702

(71) Applicant: Ractigen Therapeutics
Nantong, Jiangsu 226400 (CN)

(72) Inventors:
  • GAN, Zubao
    Nantong, Jiangsu 226400 (CN)
  • LI, Longcheng
    Nantong, Jiangsu 226400 (CN)

(74) Representative: Høiberg P/S 
Adelgade 12
1304 Copenhagen K
1304 Copenhagen K (DK)

   


(54) OLIGONUCLEOTIDE DELIVERY ENHANCING COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS USING THE SAME