(19)
(11) EP 4 543 914 A1

(12)

(43) Date of publication:
30.04.2025 Bulletin 2025/18

(21) Application number: 23733004.8

(22) Date of filing: 21.06.2023
(51) International Patent Classification (IPC): 
C07K 16/06(2006.01)
A61K 39/395(2006.01)
 A61P 1/16(2006.01)
(52) Cooperative Patent Classification (CPC):
C07K 16/06; A61P 1/16; A61K 2039/505
(86) International application number:
PCT/EP2023/066848
(87) International publication number:
WO 2023/247643 (28.12.2023 Gazette 2023/52)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
KH MA MD TN

(30) Priority: 21.06.2022 EP 22180104

(71) Applicant: Katholieke Universiteit Leuven
3000 Leuven (BE)

(72) Inventors:
  • MARQUES, Pedro Elias
    3010 Kessel-Lo (BE)
  • SILVÉRIO DE MATTOS, Matheus
    3000 Leuven (BE)
  • VANDENDRIESSCHE, Sofie
    3001 Heverlee (BE)
  • PROOST, Paul
    3210 Lubbeek (BE)

(74) Representative: Arnold & Siedsma 
Bezuidenhoutseweg 57
2594 AC The Hague
2594 AC The Hague (NL)

   


(54) USE OF NATURAL ANTIBODIES IN NECROTIC CELL DEBRIS CLEARANCE AND LIVER REPAIR DURING NECROTIC LIVER INJURY