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(11)

EP 4 551 603 A1

(12)

(43) Date of publication: 14.05.2025 Bulletin 2025/20 (21) Application number: 23742383.5 (22) Date of filing: 05.07.2023

(51) International Patent Classification (IPC):  C07K 16/28(2006.01) C12N 5/0783(2010.01) C07K 14/725(2006.01) A61K 39/00(2006.01) (52) Cooperative Patent Classification (CPC): C07K 16/2851; C07K 16/2866; C07K 16/2854; C07K 2317/622; C07K 2317/22; C07K 2317/31; C07K 2319/33; C07K 2319/03; A61K 2039/5156; C07K 14/7051; C12N 2510/00; C07K 14/70578; A61K 2239/10; A61K 2239/29; A61P 35/02; A61K 2239/48; A61K 40/421; A61K 40/4219; A61K 40/4254; A61K 40/31; A61K 40/11 (86) International application number: PCT/GB2023/051774 (87) International publication number: WO 2024/009093 (11.01.2024 Gazette 2024/02)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 06.07.2022 GB 202209920 (71) Applicant: Autolus Limited London W12 7FP (GB)	(72) Inventors: GHORASHIAN, Sara London W12 7FP (GB) HAZELTON, Warren London W12 7FP (GB) (74) Representative: D Young & Co LLP  3 Noble Street London EC2V 7BQ London EC2V 7BQ (GB)