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(11)

EP 4 554 619 A1

(12)

(43) Date of publication: 21.05.2025 Bulletin 2025/21 (21) Application number: 23754067.9 (22) Date of filing: 14.07.2023

(51) International Patent Classification (IPC):  A61K 39/395(2006.01) C07K 16/00(2006.01) (52) Cooperative Patent Classification (CPC): C07K 16/00; C12R 2001/885; C07K 2317/14; A61K 39/39591; C07K 2317/94; C07K 14/8114; C07K 14/415; C12R 2001/125 (86) International application number: PCT/US2023/070192 (87) International publication number: WO 2024/015953 (18.01.2024 Gazette 2024/03)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 15.07.2022 US 202263389472 P (71) Applicant: Danisco US Inc. Palo Alto, California 94304 (US)	(72) Inventors: HENG, Meng Hong Palo Alto, California 94304 (US) ESTELL, David A. Palo Alto, California 94304 (US) KIM, Steven Sungjin Palo Alto, California 94304 (US) LATONE, Jacob Andrew Palo Alto, California 94304 (US) MILLER, Michael C. Palo Alto, California 94304 (US) (74) Representative: Mewburn Ellis LLP  Aurora Building Counterslip Bristol BS1 6BX Bristol BS1 6BX (GB)