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EP 4 554 620 A1

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(43) Date of publication: 21.05.2025 Bulletin 2025/21 (21) Application number: 23839071.0 (22) Date of filing: 14.07.2023

(51) International Patent Classification (IPC):  A61K 39/395(2006.01) (52) Cooperative Patent Classification (CPC): Y02A 50/30; C07K 2317/24; C07K 16/2803; C07K 2317/92; C07K 2317/55; C07K 2299/00; C07K 2317/30; C07K 2317/41; C07K 2317/52; C07K 2317/732; C07K 2317/734; C07K 2317/70; A61K 2039/507; C07K 16/2818; A61K 2039/505 (86) International application number: PCT/CN2023/107563 (87) International publication number: WO 2024/012584 (18.01.2024 Gazette 2024/03)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 15.07.2022 WO PCT/CN2022/105904 30.03.2023 WO PCT/CN2023/084985 (71) Applicant: BeiGene Switzerland GmbH 4051 Basel (CH)	(72) Inventors: DING, Xiao Beijing 102206 (CN) REN, Zhiying Beijing 102206 (CN) SONG, Jing Beijing 102206 (CN) SUN, Jian Beijing 102206 (CN) XUE, Liu Beijing 102206 (CN) YANG, Xiao Beijing 102206 (CN) ZHANG, Jing Beijing 102206 (CN) CHEN, Xin Beijing 102206 (CN) (74) Representative: Mewburn Ellis LLP  Aurora Building Counterslip Bristol BS1 6BX Bristol BS1 6BX (GB)