(19)
(11) EP 4 554 939 A1

(12)

(43) Date of publication:
21.05.2025 Bulletin 2025/21

(21) Application number: 23744697.6

(22) Date of filing: 12.07.2023
(51) International Patent Classification (IPC): 
C07D 401/14(2006.01)
A61P 9/00(2006.01)
C07D 417/14(2006.01)
A61K 31/506(2006.01)
(52) Cooperative Patent Classification (CPC):
C07D 417/14; C07D 401/14; A61P 9/00
(86) International application number:
PCT/EP2023/069263
(87) International publication number:
WO 2024/013209 (18.01.2024 Gazette 2024/03)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
KH MA MD TN

(30) Priority: 13.07.2022 US 202263368268 P

(71) Applicant: Astrazeneca AB
151 85 Södertälje (SE)

(72) Inventor:
  • SERRANO-WU, Michael H.
    Belmont, Massachusetts 02478 (US)

(74) Representative: AstraZeneca Intellectual Property 
Eastbrook House Shaftesbury Road
Cambridge CB2 8BF
Cambridge CB2 8BF (GB)

   


(54) PCSK9 INHIBITORS AND METHODS OF USE THEREOF