(19)
(11) EP 4 558 139 A1

(12)

(43) Date of publication:
28.05.2025 Bulletin 2025/22

(21) Application number: 23753962.2

(22) Date of filing: 12.07.2023
(51) International Patent Classification (IPC): 
A61K 31/404(2006.01)
A61K 31/42(2006.01)
A61K 31/655(2006.01)
A61P 35/04(2006.01)
 A61K 31/41(2006.01)
A61K 31/47(2006.01)
A61K 45/06(2006.01)
(52) Cooperative Patent Classification (CPC):
A61K 31/47; A61K 31/404; A61K 31/655; A61K 31/42; A61K 31/41; A61K 45/06; A61P 35/04
 
C-Sets:
  1. A61K 31/41, A61K 2300/00;
  2. A61K 31/47, A61K 2300/00;
  3. A61K 31/404, A61K 2300/00;
  4. A61K 31/655, A61K 2300/00;
  5. A61K 31/42, A61K 2300/00;
(86) International application number:
PCT/IB2023/057151
(87) International publication number:
WO 2024/018334 (25.01.2024 Gazette 2024/04)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
KH MA MD TN

(30) Priority: 22.07.2022 PL 44181622

(71) Applicants:
  • Uniwersytet Medyczny w Lodzi
    90-419 Lodz (PL)
  • Sobierajska, Katarzyna Ewa
    03-185 Warszawa (PL)
  • Ciszewski, Wojciech Michal
    95-050 Konstantynów Lodzki (PL)

(72) Inventors:
  • SOBIERAJSKA, Katarzyna Ewa
    03-185 Warszawa (PL)
  • CISZEWSKI, Wojciech Micha
    95-050 Konstantynów ódzki (PL)

(74) Representative: Kawczynska, Marta Joanna 
Polservice Kancelaria Rzecznikow Patentowych sp. z o.o. Bobrowiecka 8
00-728 Warszawa
00-728 Warszawa (PL)

   


(54) COMBINATION COMPRISING A GGT1 INHIBITOR AND A CYSLTR1 ANTAGONIST AND USE THEREOF IN THE TREATMENT OF INVASIVE STAGES OF CANCER