(19)
(11) EP 4 558 171 A1

(12)

(43) Date of publication:
28.05.2025 Bulletin 2025/22

(21) Application number: 23843924.4

(22) Date of filing: 21.07.2023
(51) International Patent Classification (IPC): 
A61K 39/215(2006.01)
A61P 31/14(2006.01)
A61K 39/285(2006.01)
C12N 15/863(2006.01)
(52) Cooperative Patent Classification (CPC):
A61P 31/14; C12N 15/86; C12N 2710/24143; C07K 14/005; C12N 2770/20022; C12N 2770/20034; C12N 2710/24134; A61K 39/12; A61K 2039/5252; A61P 31/20; A61K 2039/575; A61K 2039/572; A61K 2039/70; A61K 2039/5254
(86) International application number:
PCT/US2023/070704
(87) International publication number:
WO 2024/020545 (25.01.2024 Gazette 2024/04)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
KH MA MD TN

(30) Priority: 22.07.2022 US 202263369199 P
09.08.2022 US 202263370922 P
24.10.2022 US 202263380718 P

(71) Applicant: City of Hope
Duarte, CA 91010-3000 (US)

(72) Inventors:
  • DIAMOND, Don J.
    Duarte, California 91010-3000 (US)
  • WUSSOW, Felix
    Duarte, California 91010-3000 (US)
  • CHIUPPESI, Flavia
    Duarte, California 91010-3000 (US)

(74) Representative: HGF 
HGF Limited 1 City Walk
Leeds LS11 9DX
Leeds LS11 9DX (GB)

   


(54) SYNTHETIC MODIFIED VACCINIA ANKARA VACCINES TO STIMULATE ORTHOPOX AND MONKEYPOX VIRUS IMMUNITY