(19)

(11)

EP 4 558 181 A1

(12)

(43) Date of publication: 28.05.2025 Bulletin 2025/22 (21) Application number: 23739273.3 (22) Date of filing: 07.07.2023

(51) International Patent Classification (IPC):  A61L 2/14(2006.01) H05H 1/26(2006.01) B08B 7/00(2006.01) (52) Cooperative Patent Classification (CPC): A61L 2/14; A61L 2202/17; A61L 2202/24; B08B 7/0035; H01J 37/32192; H01J 37/32403; H01J 37/32853; H01J 37/32862 (86) International application number: PCT/EP2023/068900 (87) International publication number: WO 2024/017676 (25.01.2024 Gazette 2024/04)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 22.07.2022 EP 22306097 22.07.2022 US 202217871122 (71) Applicants: Aurora 76000 Rouen (FR) Université De Reims Champagne-Ardenne 51100 Reims (FR)	(72) Inventors: PARIAS, Thomas 76000 ROUEN (FR) LE BRAS, Florian 76000 ROUEN (FR) GELLÉ, Marie-Paule 51100 Reims (FR) (74) Representative: Icosa  83 avenue Denfert-Rochereau 75014 Paris 75014 Paris (FR)