(19)

(11)

EP 4 558 485 A1

(12)

(43) Date of publication: 28.05.2025 Bulletin 2025/22 (21) Application number: 23752144.8 (22) Date of filing: 17.07.2023

(51) International Patent Classification (IPC):  C07D 233/64(2006.01) C07D 243/08(2006.01) C07D 263/32(2006.01) A61K 31/495(2006.01) A61K 31/4164(2006.01) C07D 243/02(2006.01) C07D 257/04(2006.01) C07D 271/107(2006.01) A61K 31/4245(2006.01) A61P 35/00(2006.01) (52) Cooperative Patent Classification (CPC): C07D 263/32; C07D 271/107; C07D 257/04; C07D 233/64; C07D 243/02; C07D 243/08; A61P 35/00; A61K 31/4164; A61K 31/4245; A61K 45/06; A61K 31/4178; A61K 31/422; A61K 31/41; A61K 31/497; A61K 31/4015; A61K 31/501; C07D 233/58; C07D 403/10; C07D 413/10   C-Sets: A61K 31/41, A61K 2300/00; A61K 31/497, A61K 2300/00; A61K 31/4015, A61K 2300/00; A61K 31/501, A61K 2300/00; A61K 31/4164, A61K 2300/00; A61K 31/4245, A61K 2300/00; A61K 31/4178, A61K 2300/00; A61K 31/422, A61K 2300/00; (86) International application number: PCT/US2023/070353 (87) International publication number: WO 2024/020350 (25.01.2024 Gazette 2024/04)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 21.07.2022 US 202263369036 P (71) Applicant: Sporos Biodiscovery, Inc. Houston, Texas 77025 (US)	(72) Inventors: MULLER, Florian Houston, TX 77025 (US) MORLEY, Andrew Houston, TX 77025 (US) SHACHAM, Sharon Houston, TX 77025 (US) (74) Representative: HGF  HGF Limited 1 City Walk Leeds LS11 9DX Leeds LS11 9DX (GB)