(19)

(11)

EP 4 558 601 A2

(12)

(88) Date of publication A3: 18.04.2024 (43) Date of publication: 28.05.2025 Bulletin 2025/22 (21) Application number: 23752104.2 (22) Date of filing: 18.07.2023

(51) International Patent Classification (IPC):  C12M 1/24(2006.01) C12M 1/00(2006.01) G01N 35/00(2006.01) B01L 3/00(2006.01) C12M 1/36(2006.01) G01N 35/04(2006.01) (52) Cooperative Patent Classification (CPC): C12M 41/48; C12M 23/08; C12M 41/14; G01N 35/0099; B01L 1/025; B01L 9/06; B01L 2300/027; B01L 3/5453; B01L 2200/143 (86) International application number: PCT/US2023/028036 (87) International publication number: WO 2024/020035 (25.01.2024 Gazette 2024/04)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 19.07.2022 US 202263390535 P 14.12.2022 US 202263432533 P 28.04.2023 US 202363890968 P (71) Applicant: Becton, Dickinson and Company Franklin Lakes, NJ 07417-1880 (US)

(72) Inventors: POHL, Brent Ronald Timonium, MD 21093 (US) JASANI, Anand Parsippany, NJ 07054 (US) SKEVINGTON, Edward M. Stewartstown, PA 17363 (US) ARMSTRONG, Robert Edward Hunt Valley, MD 21030 (US) LIVINGSTON, Dwight Fallston, MD 21047 (US) HANSEN, Timothy Roy Spring Grove, PA 17362 (US) GODSCHALL, Christopher B. Ellicott City, MD 21043 (US) FEIJEN, Franciscus Hermannus 8926RM Leeuwarden (NL) HERR, Joshua Phoenix, MD 21131 (US) RAGHUNANDAN, Sindhushree Baltimore, MD 21230 (US) LACHANCE, Stephen Robert Cockeysville, MD 21030 (US) RUSHTON, Paul London EC3V 0XL (GB) TURNER, David J. York, PA 17403 (US) RENOLL, Mark A. York, PA 17403 (US) SWECKER, Matthew Raleigh, NC 27606 (US) PETERKEN, Luke Abingdon, MD 21009 (US) MATTA, Rita Morristown, NJ 07960 (US) (74) Representative: dompatent von Kreisler Selting Werner - Partnerschaft von Patent- und Rechtsanwälten mbB  Deichmannhaus am Dom Bahnhofsvorplatz 1 50667 Köln 50667 Köln (DE)