(19)
(11) EP 4 558 624 A2

(12)

(88) Date of publication A3:
29.02.2024

(43) Date of publication:
28.05.2025 Bulletin 2025/22

(21) Application number: 23754608.0

(22) Date of filing: 17.07.2023
(51) International Patent Classification (IPC): 
C12N 9/22(2006.01)
C12N 15/113(2010.01)
C12N 15/10(2006.01)
C12N 15/90(2006.01)
(52) Cooperative Patent Classification (CPC):
C12N 9/22; C12N 15/88; C12N 15/907; C12Y 301/00
(86) International application number:
PCT/US2023/070339
(87) International publication number:
WO 2024/020346 (25.01.2024 Gazette 2024/04)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
KH MA MD TN

(30) Priority: 18.07.2022 US 202263368722 P
18.07.2022 US 202263368724 P
18.07.2022 US 202263368726 P
18.07.2022 US 202263368728 P
18.07.2022 US 202263368730 P
18.07.2022 US 202263368731 P
18.07.2022 US 202263368734 P
18.07.2022 US 202263368735 P
18.07.2022 US 202263368736 P
18.07.2022 US 202263368737 P
18.07.2022 US 202263368738 P
18.07.2022 US 202263368741 P
18.07.2022 US 202263368742 P
18.07.2022 US 202263368744 P
07.04.2023 US 202318297346
10.04.2023 US 202363495198 P

(71) Applicant: Renagade Therapeutics Management Inc.
Cambridge, Massachusetts 02139 (US)

(72) Inventors:
  • GASIUNAS, Giedrius
    10257 Vilnius (LT)
  • LADHA, Alim
    Cambridge, MA 02139 (US)
  • PRESNYAK, Vladimir
    Cambridge, MA 02139 (US)
  • JAYARAMAN, Muthusamy
    Cambridge, MA 02139 (US)
  • NARAYANAN, Elisabeth
    Watertown, MA 02472 (US)

(74) Representative: Atkins, James Gordon John et al
Kilburn & Strode LLP Lacon London 84 Theobalds Road
London WC1X 8NL
London WC1X 8NL (GB)

   


(54) GENE EDITING COMPONENTS, SYSTEMS, AND METHODS OF USE