(19)
(11) EP 4 558 627 A1

(12)

(43) Date of publication:
28.05.2025 Bulletin 2025/22

(21) Application number: 23842252.1

(22) Date of filing: 17.07.2023
(51) International Patent Classification (IPC): 
C12N 9/22(2006.01)
C12N 15/87(2006.01)
 C12N 15/10(2006.01)
C07K 14/435(2006.01)
(52) Cooperative Patent Classification (CPC):
C12N 9/22; C12N 15/90; C12N 2750/14143; A61K 48/005; C12N 15/102; C12N 15/70; C12N 9/1241; C12N 15/52; C12N 2310/20
(86) International application number:
PCT/CN2023/107697
(87) International publication number:
WO 2024/017189 (25.01.2024 Gazette 2024/04)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
KH MA MD TN

(30) Priority: 18.07.2022 WO PCT/CN2022/106290
05.06.2023 WO PCT/CN2023/098324

(71) Applicants:
  • Beijing Institute for Stem Cell and Regenerative Medicine
    Beijing 100101 (CN)
  • Institute Of Zoology, Chinese Academy Of Sciences
    Beijing 100101 (CN)

(72) Inventors:
  • WANG, Haoyi
    Beijing 100100 (CN)
  • XIANG, Guanghai
    Beijing 100100 (CN)
  • ZHANG, Yong
    Beijing 100101 (CN)
  • LI, Yuanqing
    Beijing 100101 (CN)
  • HUO, Yongyuan
    Beijing 100100 (CN)
  • SUN, Jing
    Beijing 100100 (CN)

(74) Representative: Michalski Hüttermann & Partner Patentanwälte mbB 
Kaistraße 16A
40221 Düsseldorf
40221 Düsseldorf (DE)

   


(54) TNPB-BASED GENOME EDITOR