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EP 4 558 629 A2

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(88) Date of publication A3: 10.05.2024 (43) Date of publication: 28.05.2025 Bulletin 2025/22 (21) Application number: 23843877.4 (22) Date of filing: 20.07.2023

(51) International Patent Classification (IPC):  C12N 9/22(2006.01) C12N 15/113(2010.01) C12N 5/074(2010.01) A61P 3/06(2006.01) C12N 5/071(2010.01) (52) Cooperative Patent Classification (CPC): C12N 2310/20; C12N 9/22; C07K 14/515; C12N 15/1136; A61K 31/7105   C-Sets: A61K 31/7105, A61K 2300/00; (86) International application number: PCT/US2023/070583 (87) International publication number: WO 2024/020484 (25.01.2024 Gazette 2024/04)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 20.07.2022 US 202263368926 P 02.12.2022 US 202263385944 P 29.03.2023 US 202363492808 P (71) Applicant: Emendobio Inc. Wilmington, DE 19805 (US)	(72) Inventor: EMMANUEL, Rafi 7236710 Ramla (IL) (74) Representative: Schiweck Weinzierl Koch Patentanwälte Partnerschaft mbB  Ganghoferstraße 68 B 80339 München 80339 München (DE)