(19)

(11)

EP 4 561 595 A2

(12)

(88) Date of publication A3: 14.03.2024 (43) Date of publication: 04.06.2025 Bulletin 2025/23 (21) Application number: 23847280.7 (22) Date of filing: 26.07.2023

(51) International Patent Classification (IPC):  A61K 35/51(2015.01) C12N 5/073(2010.01) A61K 9/00(2006.01) A61K 35/50(2015.01) (52) Cooperative Patent Classification (CPC): A61K 35/51; A61K 38/00 (86) International application number: PCT/US2023/028633 (87) International publication number: WO 2024/025912 (01.02.2024 Gazette 2024/05)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 26.07.2022 US 202217873383 (71) Applicant: Biostem Technologies, Inc. Pompano Beach, FL 33064 (US)	(72) Inventors: WESTON, Wendy, W. Coral Springs, FL 33071 (US) HOUSE, Michelle, R. Palm Beach, FL 33409 (US) MATUSZEWSKI, Jason, V. Boca Raton, FL 33428 (US) (74) Representative: Cabinet Nony  11 rue Saint-Georges 75009 Paris 75009 Paris (FR)