(19)

(11)

EP 4 562 168 A1

(12)

(43) Date of publication: 04.06.2025 Bulletin 2025/23 (21) Application number: 23758374.5 (22) Date of filing: 28.07.2023

(51) International Patent Classification (IPC):  C12N 15/82(2006.01) A01H 5/00(2018.01) C07K 14/435(2006.01) (52) Cooperative Patent Classification (CPC): C12N 15/8286; C12N 15/8218; C07K 14/43563; Y02A 40/146 (86) International application number: PCT/IB2023/000435 (87) International publication number: WO 2024/023578 (01.02.2024 Gazette 2024/05)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 28.07.2022 US 202263393166 P (71) Applicant: Institut Pasteur 75015 Paris (FR)	(72) Inventors: SALEH, Maria Carla 75015 Paris (FR) FLETCHER, Sabrina Johanna 10126 Turin (IT) (74) Representative: Regimbeau  20, rue de Chazelles 75847 Paris Cedex 17 75847 Paris Cedex 17 (FR)