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EP 4 562 599 A1

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(43) Date of publication: 04.06.2025 Bulletin 2025/23 (21) Application number: 23847475.3 (22) Date of filing: 24.07.2023

(51) International Patent Classification (IPC):  G06T 7/00(2017.01) G06T 7/62(2017.01) G16H 30/40(2018.01) G06N 3/04(2023.01) G16H 70/60(2018.01) G06V 10/26(2022.01) G06V 10/25(2022.01) (52) Cooperative Patent Classification (CPC): G16H 30/40; G06V 10/26; G06T 7/0012; G06T 7/11; G06T 7/136; G06T 2207/20081; G06T 2207/20084; G06T 2207/30016; G06T 2207/30096; G06T 2207/10081; G06T 2207/10088; G06T 2207/30061; G16H 30/20; G16H 40/67; G16H 50/20; G16H 50/70; G16H 20/00; G06V 20/69; G06V 2201/03; G06N 20/00 (86) International application number: PCT/US2023/070816 (87) International publication number: WO 2024/026255 (01.02.2024 Gazette 2024/05)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 25.07.2022 US 202263392007 P (71) Applicants: Memorial Sloan Kettering Cancer Center New York, NY 10065 (US) Memorial Hospital for Cancer and Allied Diseases New York, NY 10065 (US) Sloan-kettering Institute For Cancer Research New York, NY 10065 (US)

(72) Inventors: SWINBURNE, Nathaniel Cuthbert New York, New York 10065 (US) YADAV, Vivek New York, New York 10065 (US) (74) Representative: Barker Brettell LLP  100 Hagley Road Edgbaston Birmingham B16 8QQ Birmingham B16 8QQ (GB)