(19)
(11) EP 4 565 256 A2

(12)

(88) Date of publication A3:
10.05.2024

(43) Date of publication:
11.06.2025 Bulletin 2025/24

(21) Application number: 23850990.5

(22) Date of filing: 04.08.2023
(51) International Patent Classification (IPC): 
A61K 38/20(2006.01)
C07K 19/00(2006.01)
A61K 39/385(2006.01)
C07K 14/54(2006.01)
A61K 38/19(2006.01)
(52) Cooperative Patent Classification (CPC):
C07K 14/54; C07K 2319/04; C07K 2319/01; C12N 15/62; C07K 2319/50; C07K 2319/30; A61K 38/00
(86) International application number:
PCT/US2023/071663
(87) International publication number:
WO 2024/031046 (08.02.2024 Gazette 2024/06)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
KH MA MD TN

(30) Priority: 05.08.2022 US 202263395476 P
02.05.2023 US 202363463505 P

(71) Applicant: Fuse Biotherapeutics Inc.
Woburn, Massachusetts 01801 (US)

(72) Inventors:
  • ZHOU, Xueyuan
    Belmont, Massachusetts 02478 (US)
  • RABINOVICH, Brian
    Winchester, Massachusetts 01890 (US)
  • TAKIMOTO, Jeffrey
    Cerritos, California 90703 (US)

(74) Representative: Hutter, Anton et al
Venner Shipley LLP 5 Stirling House Stirling Road The Surrey Research Park
Guildford GU2 7RF
Guildford GU2 7RF (GB)

   


(54) IL-18 FUSION PROTEINS AND METHODS OF PRODUCING IL-18