(19)

(11)

EP 4 565 274 A2

(12)

(88) Date of publication A3: 11.04.2024 (43) Date of publication: 11.06.2025 Bulletin 2025/24 (21) Application number: 23850972.3 (22) Date of filing: 03.08.2023

(51) International Patent Classification (IPC):  A61K 47/30(2006.01) A61J 3/07(2006.01) A61J 3/00(2006.01) A61K 9/52(2006.01) (52) Cooperative Patent Classification (CPC): A61K 9/0065; A61K 47/02; A61K 47/34 (86) International application number: PCT/US2023/071617 (87) International publication number: WO 2024/031023 (08.02.2024 Gazette 2024/06)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 03.08.2022 US 202263370366 P (71) Applicant: Lyndra Therapeutics, Inc. Watertown, Massachusetts 02472 (US)	(72) Inventors: KOEPPEN, Ryan Watertown, Massachusetts 02472 (US) GRANT, Tyler Watertown, Massachusetts 02472 (US) CHADWICK, Samuel Watertown, Massachusetts 02472 (US) DUFOUR, David C. Watertown, Massachusetts 02472 (US) RYDE, Erik Robert Waldemar Watertown, Massachusetts 02472 (US) (74) Representative: Mewburn Ellis LLP  Aurora Building Counterslip Bristol BS1 6BX Bristol BS1 6BX (GB)