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EP 4 565 331 A1

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(43) Date of publication: 11.06.2025 Bulletin 2025/24 (21) Application number: 23754854.0 (22) Date of filing: 28.07.2023

(51) International Patent Classification (IPC):  A61P 35/00(2006.01) C07K 16/32(2006.01) A61P 25/00(2006.01) C07K 16/18(2006.01) G01N 33/573(2006.01) C07K 16/28(2006.01) (52) Cooperative Patent Classification (CPC): C07K 16/32; C07K 16/2896; C07K 2317/31; C07K 2317/64; C07K 2317/565; C07K 2317/56; C07K 2317/622; C07K 2317/35; A61K 2039/505; C07K 2317/732; A61K 2039/54; A61P 35/00; A61P 25/00 (86) International application number: PCT/IB2023/057723 (87) International publication number: WO 2024/028732 (08.02.2024 Gazette 2024/06)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 05.08.2022 US 202263395389 P (71) Applicant: Janssen Biotech, Inc. Horsham, PA 19044 (US)

(72) Inventors: CHEUNG, Wan Cheung Raritan, New Jersey 08869 (US) EDAVETTAL, Suzanne Horsham, Pennsylvania 19044 (US) PATTERSON, James Raritan, New Jersey 08869 (US) BUSCHMAN, Matthew Raritan, New Jersey 08869 (US) SCHEER, Justin Raritan, New Jersey 08869 (US) SHA, Fern Raritan, New Jersey 08869 (US) TANEJA, Isha Raritan, New Jersey 08869 (US) (74) Representative: Carpmaels & Ransford LLP  One Southampton Row London WC1B 5HA London WC1B 5HA (GB)