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EP 4 565 585 A1

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(43) Date of publication: 11.06.2025 Bulletin 2025/24 (21) Application number: 23761384.9 (22) Date of filing: 02.08.2023

(51) International Patent Classification (IPC):  C07D 471/04(2006.01) A61K 31/437(2006.01) A61P 35/00(2006.01) C07D 487/04(2006.01) A61K 31/4985(2006.01) (52) Cooperative Patent Classification (CPC): C07D 471/04; C07D 487/04; A61P 35/00 (86) International application number: PCT/US2023/071535 (87) International publication number: WO 2024/030968 (08.02.2024 Gazette 2024/06)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 03.08.2022 US 202263370307 P (71) Applicant: Bristol-Myers Squibb Company Princeton, NJ 08543 (US)

(72) Inventors: QIAO, Jennifer X. Princeton, New Jersey 08543 (US) WILLIAMS, David K. Princeton, New Jersey 08543 (US) GILL, Patrice Princeton, New Jersey 08543 (US) DHAR, T.G. Murali Princeton, New Jersey 08543 (US) TOKARSKI, John S. Princeton, New Jersey 08543 (US) GAVAI, Ashvinikumar V. Princeton, New Jersey 08543 (US) (74) Representative: Carpmaels & Ransford LLP  One Southampton Row London WC1B 5HA London WC1B 5HA (GB)